Search on: NITRIC OXIDE RECEPTORS 
Descriptors Found: 1
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Descriptor English:   Soluble Guanylyl Cyclase 
Descriptor Spanish:   Guanilil Ciclasa Soluble 
Descriptor Portuguese:   Guanilil Ciclase Solúvel 
Synonyms English:   Nitric Oxide Receptor
Nitric Oxide Receptors
Nitric Oxide-Sensitive Guanylyl Cyclase
Receptor, Nitric Oxide
Soluble Guanylate Cyclase
Soluble Guanylyl Cyclase, alpha Subunit
Soluble Guanylyl Cyclase, beta Subunit
Cyclase, Soluble Guanylate
Cyclase, Soluble Guanylyl
Guanylate Cyclase, Soluble
Guanylyl Cyclase, Soluble
Nitric Oxide Sensitive Guanylyl Cyclase
Oxide Receptor, Nitric
Oxide Receptors, Nitric
Receptors, Nitric Oxide  
Tree Number:   D08.811.520.650.600.750
D12.644.360.350.500
D12.776.476.350.500
Definition English:   A mammalian enzyme composed of a heterodimer of alpha and beta subunits. Each subunit consists of four domains; N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four domains are homologous proteins with a similar conformation of functional domains. Soluble guanylate cyclase catalyzes the formation of cyclic GMP from GTP, and is a key enzyme of the nitric oxide signaling pathway involved in the regulation of a variety of biological and physiological processes in mammals. 
History Note English:   2017 (2016) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56499 
Unique Identifier:   D000071756 

Occurrence in VHL: 		 

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